The Long-term Outlook for Essential Thrombocythemia

Ruxolitinib for essential thrombocythemia?

Essential thrombocythemia beyond the first decade: life expectancy, long-term complication rates, and prognostic factors.

OBJECTIVE To describe the long-term natural history of essential thrombocythemia (ET) in terms of life expectancy, risk of disease transformation Into a more aggressive myeloid disorder, and prognostic factors for both survival and disease complications. PATIENTS AND METHODS The study population consisted of a consecutive cohort of patients seen at the Mayo Clinic In Rochester, Minn, in whom ...

Essential thrombocythemia

Essential thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by a sustained elevation of platelet number with a tendency for thrombosis and hemorrhage. The prevalence in the general population is approximately 30/100,000. The median age at diagnosis is 65 to 70 years, but the disease may occur at any age. The female to male ratio is about 2:1. The clinical pictu...

The Long-Term Outlook for Salmon Returns to Alaska

With the exception of some western Alaska stocks, Alaska’s salmon populations are numerically healthy. However, even fi sheries on abundant stocks are suffering economically due to sharp declines in the value of the catch. The abundance of Alaskan salmon stocks has fl uctuated greatly, both in modern times and prehistorically. These fl uctuations are thought to be caused by multi-decadal change...

Percutaneous tracheostomy--long-term outlook, a review.

OBJECTIVE To review the techniques and long term complications of the various techniques of percutaneous tracheostomy in the critically ill patient. DATA SOURCES A review of studies reported on the various percutaneous tracheostomy techniques. SUMMARY OF REVIEW A tracheostomy is frequently performed in the critically ill patient when prolonged mechanical ventilation, airway protection and p...